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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC14
All Species:
23.64
Human Site:
S446
Identified Species:
43.33
UniProt:
Q8IZN3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZN3
NP_078906.2
488
53388
S446
L
T
P
D
E
A
P
S
P
P
R
L
L
A
A
Chimpanzee
Pan troglodytes
XP_001143896
464
50937
S422
L
T
P
D
E
A
P
S
P
P
R
L
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001093039
488
53343
S446
L
T
P
D
E
A
P
S
P
P
R
L
L
A
A
Dog
Lupus familis
XP_854971
420
45636
S379
L
T
P
E
E
A
P
S
P
P
R
L
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQQ1
489
53640
S447
L
T
P
D
E
A
P
S
P
P
R
M
L
G
A
Rat
Rattus norvegicus
Q2TGJ1
386
41641
L345
C
A
V
L
C
G
P
L
P
P
S
L
I
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232232
491
53709
S449
L
T
P
E
E
A
P
S
P
P
G
M
L
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038652
513
56361
P471
S
P
E
E
T
P
S
P
P
A
P
L
P
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137936
693
74989
E642
A
E
Q
V
K
S
A
E
R
L
R
M
L
H
D
Honey Bee
Apis mellifera
XP_395517
664
74472
T566
L
C
P
N
D
S
S
T
T
N
S
V
S
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796142
543
59493
E501
L
L
P
A
G
H
G
E
E
Q
C
D
T
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SB58
407
46728
R366
T
L
D
I
D
H
E
R
A
G
S
I
R
T
E
Baker's Yeast
Sacchar. cerevisiae
Q06551
359
41080
M318
K
G
S
F
L
K
N
M
G
H
L
M
L
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.8
80.9
N.A.
94.8
50.4
N.A.
N.A.
89.6
N.A.
66.6
N.A.
37.2
41.8
N.A.
41.9
Protein Similarity:
100
95
100
82.7
N.A.
97.7
58.6
N.A.
N.A.
93.8
N.A.
76.2
N.A.
50.2
51.6
N.A.
57
P-Site Identity:
100
100
100
86.6
N.A.
86.6
26.6
N.A.
N.A.
66.6
N.A.
20
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
N.A.
86.6
N.A.
26.6
N.A.
33.3
46.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.7
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
47
8
0
8
8
0
0
0
31
39
% A
% Cys:
8
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
8
31
16
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
8
8
24
47
0
8
16
8
0
0
0
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
8
8
0
8
8
8
0
0
8
8
% G
% His:
0
0
0
0
0
16
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
62
16
0
8
8
0
0
8
0
8
8
47
62
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
31
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
62
0
0
8
54
8
62
54
8
0
8
8
16
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
47
0
8
8
8
% R
% Ser:
8
0
8
0
0
16
16
47
0
0
24
0
8
0
8
% S
% Thr:
8
47
0
0
8
0
0
8
8
0
0
0
8
8
0
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _